Oestradiol

Blood Sciences Test

Specimen

Serum

Units

pmol/L

Reference Range

Female

Follicular phase : 45 – 854 pmol/L
Mid-cycle : up to 1461 pmol/L
Luteal phase: 82 – 1251 pmol/L
Menopausal : up to 505 pmol/L

Male

41-159 pmol/L

Test Usage

Oral contraceptives are associated with very low levels pregnancy is associated with very high levels.

The assay is specific for oestradiol. Other oestrogens such as ethinyl oestradiol conjugated equine oestrogens (premarin) are not detected. Oestradiol is the major endogenous oestrogen in ovulating women. It rises to a pre-ovulatory peak mid-cycle, falls and then returns to a luteal phase plateau before falling again prior to menstruation. Indications for estimating oestradiol are strictly
limited:

during artificial induction of ovulation
investigation of feminising states including precocious puberty, gynaecomastia
investigation of possible pituitary-gonadal deficiency states in women.

It is not used during the early investigation of infertility, for diagnosing menopause,
for monitoring HRT (hormone replacement therapy), or for investigating irregular
menstruation.

Drug Interference

Please Note; assay interference from the drug fulvestrant (Faslodex®) may cause falsely elevated estradiol results.

Turnaround time

1 day

Availability

Local

Can be added on to an existing request up to 4 days following sample receipt

Specimen Labelling Procedure