Cardiolipin Antibodies

Blood Sciences Test

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Specimen

Serum

Special Instructions

Minimum sample volume: 3 ml

Reference Range

IgG Cardiolipin antibodies:

• Negative : <10.0 GPL U/ml
• Weak Positive : 10.0-40.0 GPL U/ml
• Positive: >40  GPL U/ml

IgM Cardiolipin antibodies:

• Negative : <10.0 MPL U/ml
• Weak Positive : 10.0-40.0 MPL U/ml
• Positive: >40 MPL U/ml

Test Usage

Anticardiolipin antibodies are present in the antiphospholipid syndrome (arterial & venous thrombosis, recurrent foetal loss, thrombocytopaenia). The antiphospholipid syndrome can be primary or secondary to a CTD such as SLE. If antiphospholipid syndrome is suspected, a lupus anticoagulant screen should always be performed regardless of the cardiolipin result.

Turnaround time

Weekly

Availability

In House

Assayed By

Royal Devon & Exeter Hospital (Wonford)

Clinical Advice

A definitive clinical diagnosis should not be based on the results of a single diagnostic method, but should only be made by the physician after all clinical and laboratory findings have been evaluated.

Clinical advice is available from the Immunology Medical Team at Derriford Hospital

T: 01752 431675

E: plh-tr.eden@nhs.net

 

Specimen Labelling Procedure