Change to Prescription of Fosfomycin

As of 01/12/15 the RD&E pharmacy will no longer supply Fosfomycin 3g sachets for community patients against a GP proforma.

There is now a licensed product available, so if you need to use Fosfomycin, prescribe in the normal way, and the patient can collect from the local pharmacist.

 

Indications:

Uncomplicated lower urinary-tract infections caused by multi-resistant organisms when there are no more suitable alternative antibacterial options available

Patients are eligible for treatment with fosfomycin if the following criteria are fulfilled:

• They must be suffering from a symptomatic UTI;
• A urine specimen must have been examined by the laboratory;
• There must be a significant growth of a fosfomycin-sensitive organism in the urine sample; and
• There must be no other more suitable oral treatment alternative, either because of bacterial resistance, or patient allergy or intolerance to suitable antimicrobials

Dosing

Adult (female): 3grams orally for 1 dose (a second dose may be given after 72hours with persistent infection and/or on the advice of microbiology)

Adult (male): 3grams orally for 1 dose, then 3grams orally after 3 days

References/Further info

RDE RX antimicrobial pages: http://app.rx-guidelines.com/Viewing/Index/171#W2pUxOTUUH

Product characteristics: http://www.mhra.gov.uk/home/groups/spcpil/documents/spcpil/con1444368450881.pdf